Inhibition of T Helper Cell Type 2 Cell Differentiation and Immunoglobulin E Response by Ligand - activated V a 14 Natural Killer T Cells
نویسندگان
چکیده
From the * CREST (Core Research for Evolution Science and Technology) Project, Japan Science and Technology Corporation, Department of Molecular Immunology, Graduate School of Medicine, Chiba University, and the ‡ Department of Developmental Immunology, Chiba University School of Medicine, 1-8-1 Inohana, Chuo-ku, Chiba 260-8670, Japan; and the § Department of Tropical Medicine, Jikei University School of Medicine, 3-25-8 Nishi-shinbashi, Minato-ku, Tokyo 105, Japan
منابع مشابه
Inhibition of T Helper Cell Type 2 Cell Differentiation and Immunoglobulin E Response by Ligand-Activated Vα14 Natural Killer T Cells
Murine Valpha14 natural killer T (NKT) cells are thought to play a crucial role in various immune responses, including infectious, allergic, and autoimmune diseases. Because Valpha14 NKT cells produce large amounts of both interleukin (IL)-4 and interferon (IFN)-gamma upon in vivo stimulation with a specific ligand, alpha-galactosylceramide (alpha-GalCer), or after treatment with anti-CD3 antib...
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